General information

Course name	Blockveranstaltung: Next Generation Sequencing to identify the disease gene in unclear neurogenetic disorders
Subtitle
Course number	340456
Semester	SoSe 2024
Current number of participants	0
maximum number of participants	6
notwendige Teilnehmeranzahl	3
Home institute	Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften (GGNB)
Courses type	Blockveranstaltung in category Teaching
First date	Monday, 17.06.2024 09:00 - 16:30
Type/Form

Lehrende

Rooms and times

No room preference: Monday, 17.06.2024 09:00 - 16:30
Tuesday, 18.06.2024 09:00 - 16:30

Fields of study

Comment/Description

In these 2 days we will give a general introduction to Next Generation Sequencing (NGS) and relevant application in clinical diagnostic, namely to solve unclear neurogenetic disorders. The focus of this course is to learn different filter strategies to extract pathogenic variants under using heredity and biological prediction tools.

Day 1:

- Introduction to NGS (library preparation, sequencing platforms, data generation and analysis)

- Introduction in basic laws of inheritance

- Analysis platform: Varbank2

- Examples of newly identified disease genes

- Practical part: Analysis of exome-seq experiment

Day 2:

- Applications in clinical diagnostic (panel / exome / genome sequencing)

- Science Breakfast (NGS in Newborns)

- Clinical Pipeline: from Patient to NGS results

- Biological interpretation of detected variants (ACMG classification system)

- Practical part: Analysis of exome-seq experiment with focus in biological interpretation

Important:

Once participation has become binding after the signing-out period, cancellation is only possible via the GGNB or GAUSS Office with a) sick certificate, or b) statement by supervisor for scientific reasons. If you do not provide this, you will be excluded from courses for the next 12 months, as well as travel grants and other financial support. No exceptions.

By signing up you agree (1) to carefully check whether you will be able to attend the course (do not register for 2 courses taking place on the same dates - the above mentioned sanctions apply!), (2) to frequently check your student e-mail account, as all information on courses will exclusively be sent to that account; (3) that your name and e-mail address may be forwarded to the course instructor(s) for communication before and after the course; (4) to complete the course evaluation; (5) inform us if you no longer wish to maintain a waiting list position; (6) that you only receive credits for attending the entire workshop - you will not get partial credits for part-time attendance.

Admission settings

The course is part of admission "GGNB_Methods_2024_SoSe_April_Juni".

You can register and sign out for methods courses in June 2024 from 1-20 April 2024. The slots will be assigned around 25 April 2024.
In exceptional circumstances, you can still sign out until 30 April 2024.
Your participation becomes binding on 2 May 2024. Thereafter, cancellation is only possible via the GGNB Office with a) sick certificate, or b) statement by supervisor (for scientific reasons). If you do not provide this, you will be excluded from courses for the next 12 months, as well as travel grants and other financial support.

By signing up you agree (1) to carefully check whether you will be able to attend the course (do not register for 2 courses taking place on the same dates – the above mentioned sanctions apply!), (2) to frequently check your student e-mail account, as all information on courses will exclusively be sent to that account; (3) that your name and e-mail address may be forwarded to the course instructor(s) for communication before and after the course; (4) to complete the course evaluation.
The following rules apply for the admission:

At least one of these conditions must be fulfilled for enrolment:
- Subject is Computer Science -PCS-
- Subject is Molekulare Biologie
- Subject is PhysicsBiologComplexSyste
- Subject is Systems Neuroscience
- Subject is Materialforschung Holz
- Subject is MolecularBiology of Cells
- Subject is Geographie
- Subject is Environmental Informatics
- Subject is Behavior and Cognition
- Subject is Theoret Computat Neurosci
- Subject is Neurowissenschaften
- Subject is IRTG 2172 - PRoTECT
- Subject is Psychologie
- Subject is Molekulare Medizin
- Subject is Umweltinformatik
- Subject is Emerging Infect. Diseases
- Subject is Genome Science
- Subject is Environmental Informatics
- Subject is Geoscience
- Subject is Biologie
- Subject is Genes in Development, Disease and Evolution
- Subject is Biologische Diversität und Ökologie
- Subject is Physik
- Subject is Microbiology-Biochemistry
- Subject is Mathematical Sciences
- Subject is Geography
- Subject is Chemie
- Subject is BioNutz-MolwissBiotechnol
- Subject is Biomol:Struc-Func-Dynamic
- Subject is Cardiovascular Science
- Subject is Catalysis Sust.Synt.CaSuS
- Subject is SensoryMotor Neuroscience
- Subject is MolecularPhysi oftheBrain
- Subject is MetalSites i.Biomolecules
At least one of these conditions must be fulfilled for enrolment:
- Degree is PromProgramm Cotutelle
- Degree is PromStudiengang Cotutelle
- Degree is Promotionsprogramm
- Degree is Promotionsstudiengang
- Degree is Promotion m.Abschlussprfg
- Degree is Promotion Cotutelle
The enrolment is possible from 01.04.2024, 00:00 to 20.04.2024, 23:59.
A defined number of seats will be assigned to these courses.
The seats in the affected courses have been assigned at 25.04.2024 on 23:59. Additional seats may be available via a wait list.
Enrolment is allowed for up to 2 courses of the admission set.

Assignment of courses:

Registration mode

The enrolment is binding, participants cannot unsubscribe themselves.

Blockveranstaltung: Next Generation Sequencing to identify the disease gene in unclear neurogenetic disorders - Details