Lecture: Statistical genetics, breeding informatics and experimental design - Details

General information

Course name	Lecture: Statistical genetics, breeding informatics and experimental design
Subtitle
Course number	740823
Semester	WiSe 2023/24
Current number of participants	27
expected number of participants	20
Home institute	Züchtungsinformatik
Courses type	Lecture in category Teaching
First date	Tuesday, 24.10.2023 16:15 - 17:45, Room: (L04 (Agrarwissenschaften-Institutsgebäude))
Type/Form

Lecturers

• UnivProf.Dr. Armin Schmitt

Tutors

• Thomas Martin Lange
• Johanna Sophie Schlüter
• Dr. Felix Heinrich

Rooms and times

(L04 (Agrarwissenschaften-Institutsgebäude))

Tuesday: 16:15 - 17:45, weekly (12x)

(L09 (Tierzucht-Institutsgebäude))

Thursday: 14:15 - 15:45, weekly (13x)

(L05 (Tierzucht-Institutsgebäude))

Tuesday, 30.01.2024 16:15 - 17:45

Fields of study

Module assignments

• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 4. Version valid from SoSe 2025 > Master-Studiengang "Integrated Plant and Animal Breeding" - Block A - Compulsory Modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 10. Version valid from WiSe 2022/23 > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Genomic selection" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 3. Version (WiSe 2024/25) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Genomic selection" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Compu Bio Bioinformatics konsekutiven Master-Studiengang "Computational Biology and Bioinformatics", 2. Version (SoSe 2023) > Master-Studiengang "Computational Biology and Bioinformatics" - Fachstudium (54 C) - Wahlpflichtmodule „Bioinformatik“ > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Angewandte Informatik konsekutiven Master-Studiengang "Angewandte Informatik", 23. Version valid from WiSe 2024/25 > Studienschwerpunkt "Bioinformatik" - Wahlpflichtmodule - Themengebiet "Biologie" (wenigstens 18 C) - Gruppe 2 > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 3. Version (WiSe 2024/25) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Other modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 1. Version (WiSe 2023/24) > Master-Studiengang "Integrated Plant and Animal Breeding" - Block A - Compulsory Modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Compu Bio Bioinformatics konsekutiven Master-Studiengang "Computational Biology and Bioinformatics", 4. Version (SoSe 2024) > Master-Studiengang "Computational Biology and Bioinformatics" - Fachstudium (54 C) - Wahlpflichtmodule „Bioinformatik“ > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Agrarwissenschaften für den konsekutiven Master-Studiengang "Agrarwissenschaften", 3. Version (WiSe 2024/25) > Master-Studiengang "Agrarwissenschaften" - Studienschwerpunkte - Schwerpunkt "Nutztierwissenschaften" - Block B > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 10. Version valid from WiSe 2022/23 > Master-Studiengang "Integrated Plant and Animal Breeding" - Block A - Compulsory Modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 2. Version (SoSe 2024) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Biological and societal context of breeding" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 4. Version valid from SoSe 2025 > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Other modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Compu Bio Bioinformatics konsekutiven Master-Studiengang "Computational Biology and Bioinformatics", 5. Version valid from WiSe 2024/25 > Master-Studiengang "Computational Biology and Bioinformatics" - Fachstudium (54 C) - Wahlpflichtmodule „Bioinformatik“ > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 2. Version (SoSe 2024) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Other modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Compu Bio Bioinformatics konsekutiven Master-Studiengang "Computational Biology and Bioinformatics", 1. Version (WiSe 2022/23) > Master-Studiengang "Computational Biology and Bioinformatics" - Fachstudium (54 C) - Wahlpflichtmodule „Bioinformatik“ > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 2. Version (SoSe 2024) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Genomic selection" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Compu Bio Bioinformatics konsekutiven Master-Studiengang "Computational Biology and Bioinformatics", 3. Version (WiSe 2023/24) > Master-Studiengang "Computational Biology and Bioinformatics" - Fachstudium (54 C) - Wahlpflichtmodule „Bioinformatik“ > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 2. Version (SoSe 2024) > Master-Studiengang "Integrated Plant and Animal Breeding" - Block A - Compulsory Modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 10. Version valid from WiSe 2022/23 > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Other modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Agrarwissenschaften für den konsekutiven Master-Studiengang "Agrarwissenschaften", 4. Version valid from SoSe 2025 > Master-Studiengang "Agrarwissenschaften" - Studienschwerpunkte - Schwerpunkt "Nutztierwissenschaften" - Block B > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 4. Version valid from SoSe 2025 > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Biological and societal context of breeding" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 1. Version (WiSe 2023/24) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Genomic selection" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Angewandte Informatik konsekutiven Master-Studiengang "Angewandte Informatik", 22. Version (WiSe 2023/24 - SoSe 2024) > Studienschwerpunkt "Bioinformatik" - Wahlpflichtmodule - Themengebiet "Biologie" (wenigstens 18 C) - Gruppe 2 > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 1. Version (WiSe 2023/24) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Biological and societal context of breeding" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 4. Version valid from SoSe 2025 > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Genomic selection" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 1. Version (WiSe 2023/24) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Other modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Agrarwissenschaften für den konsekutiven Master-Studiengang "Agrarwissenschaften", 2. Version (SoSe 2024) > Master-Studiengang "Agrarwissenschaften" - Studienschwerpunkte - Schwerpunkt "Nutztierwissenschaften" - Block B > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 3. Version (WiSe 2024/25) > Master-Studiengang "Integrated Plant and Animal Breeding" - Block A - Compulsory Modules > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding für den konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 3. Version (WiSe 2024/25) > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Biological and societal context of breeding" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Angewandte Informatik konsekutiven Master-Studiengang "Angewandte Informatik", 21. Version (WiSe 2022/23 - SoSe 2023) > Studienschwerpunkt "Bioinformatik" - Wahlpflichtmodule - Themengebiet "Biologie" (wenigstens 18 C) - Gruppe 2 > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design
• Plant animal breeding konsekutiven Master-Studiengang "Integrated Plant and Animal Breeding", 10. Version valid from WiSe 2022/23 > Double-Degree Programme "European Master of Animal Breeding and Genetics" (EMABG) - Block B - Elective compulsory modules - Study Track "Biological and societal context of breeding" > M.iPAB.0003 - Statistical genetics, breeding informatics and experimental design, valid from WiSe 2019/20 > Statistical genetics, breeding informatics and experimental design

Comment/Description

Contents:
• Gene Expression Analysis
• Genome-wide association analysis
• QTL mapping
• Statistical hypothesis testing
• Regression methods
• Analysis of variance
• Multiple testing
• Experimental designs (block designs, randomized designs, Latin squares)
• Sample size estimation
• Introduction to programming
• Fundamentals of databases

Novel biotechnological methods allow the production of very large data sets (gene
sequences, genotypes, transcriptomes) at decreasing costs. Students learn about
statistical and computational methods to use these records for breeding issues.
Furthermore, the main experimental designs to plan, implement, and evaluate targeted
and efficient experiments for data generation will be treated.

Examination requirements:
Profound knowledge of statistics and informatics methods to use them for breeding
issues.